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Putting a Foldable Microscope to the Test in the Amazon
A couple of months ago, I received an interesting package in the mail. It looked like a standard manila envelope, but inside was a device that could quite possibly revolutionize the way we view the microscopic world. I’m referring to the Foldscope, an origami-based optical microscope that is small enough to fit inside your pocket. The real kicker: the entire cost of the instrument is less than one dollar.
The Foldscope has received some recent and well-deserved media attention (the lab’s publication on this device recently made it in the top 20 papers in PlosOne for 2014) but I hadn’t seen many videos on the Foldscope being put to the test in the field. It seemed like there was a lot of potential for this invention but I wondered how it would fare on one of my expeditions through a jungle searching for unknown species. So I decided to assemble my miniature paper microscopes and travel to one of the most remote places in the world, the rainforest of the Peruvian Amazon, to give them a go.
The Results
Long story short, this device is amazing. During my time in the Amazon rainforest, I was able to investigate tiny insects, mites, fungi, and plant cells from 140x to 480x magnification without requiring a large and expensive conventional microscope.
The cells from a flower petal were recorded by connecting a cell phone to the Foldscope.
Some of the diverse arthropod specimens could potentially be new to science, so it was really exciting to document images and videos of these organisms right there in the field by connecting my phone to the Foldscope.
An unknown species of mite was documented by connecting a cell phone to the Foldscope.
A spider is infected by a parasitic fungus known as Cordyceps. The circles show regions of the fungus viewed under the Foldscope.
In the video, I investigate bizarre structures on a plant, which are known as leaf galls. These are sometimes created by insects, but they usually have to be taken back to a lab and inspected in detail under a microscope. Lucky for me, I had the Foldscope in the field! It turns out these were in fact due to insect larvae, which burrowed into the leaf and tweaked the chemistry of the plant to produce galls. Even with macro photography, I couldn’t get much detail of the larva, but at 140x magnification, under the Foldscope, I was able to document the morphology of this unknown critter.
Top left, a leaf is covered in galls. Top right, a cross-section of a gall; notice the tiny insect larva living inside! Bottom, the larva was placed under the Foldscope and viewed on my cell phone. Pictures and videos were recorded in real-time out in the Amazon rainforest.
Suspecting that the galls were formed by some sort of wasp or fly, I later got in touch with a couple of Diptera (fly) experts, Morgan Jackson (@BioInFocus) and Dr. Stephen Gaimari, who helped identify the gall-forming culprits as a possible species of fly belonging to the family Cecidomyiidae.
Final Thoughts
The research team, led by Dr. Manu Prakash, seeks to “democratize science” by developing tools that are able to scale up to match problems in global health and science education – and I believe they are doing just that with the Foldscope. This device is cheap, easy to use, and broadly applicable whether you’re a curious young student, a medical professional in the field, or someone who is interested in the numerous tiny things that surround us. Until now, I’ve never had a device that made viewing and sharing the microcosmos so accessible.
A closer look at the moss covering a tree in the tropical rainforest.
Morphology of a neotropical pseudoscorpion – all images were taken in the field with the Foldscope!
A breakdown of the unit costs for Foldscope components in volumes of 10,000 units, not including assembly costs (Cybulski, Clements, & Prakash 2014). The total cost of the Foldscope ranges from {%_CONTENIDO_%}.58 to {%_CONTENIDO_%}.97.
By Aaron Pomerantz
You can follow Aaron for more updates on Twitter @AaronPomerantz and the Stanford University Researchers @PrakashLab
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The lodge is located in the middle of the forest accessible only by boat. The experience was very unique and exciting. Service is great, and the fun part are the nature activities and tours the hotel offers for free. We had an amazing tour guide that had a lot of knowledge and was fun to spend time with. The rooms are totally open to the forest which is really cool the struggle is the there is no privacy at all in between the rooms, also food was pretty basic. All together a very unique experience. Read all
This hotel is the perfect blend of comfort and hospitality, with the natural experience. The hotel is reached by a hours boat ride from Puerto Maldonado, expertly organized and accomplished. Most staff are members of the local Esa Ejja community. The food is good and plentiful. Hot water is always available and lovely bedding features mosquito nets. There is of course no air conditioning (one side wall is open in rach room) and the electricity is off for a few hours at night affecting overhead fans, so I was glad to have brought a small battery powered fan for sleeping. But the best of the experience is the wildlife. Our expert guide Oscar Mishaja introduced us to nearly 100 bird species, along with caimans, river otters, poison dart frogs and capybara. A trip of a lifetime. Read all
Excellent experience overall— really kind and welcoming staff at every point of the journey. All transfers were well organized and smooth. Excellent and educational excursions all around the rainforest. Delicious food for every meal. We had wonderful guides- Freet and Alvaro. Enjoyed our time here! Read all
We had a surreal experience at Refugio Amazonas. From the well organized transportation to the warm welcome, hospitality and the experience of living in nature - we loved it all. Huge shout out to our guide Boris who went out of his way to ensure we had a good experience and got to watch all kinds of wild life. The meals and cocktails were delicious. And even though this place is smack in the middle of the jungle there was super fast WiFi available. We made unforgettable memories. Read all
We had an amazing time in TRC. From the guide, tours, lounge staff, food and room, everything has exceeded our expectation and like an amazing dream came true. We highly recommend to directly book with the lounge website, so that you got a private guide for your group. Special thanks to our guide Saul, who made this experience extra special! We were so impressed by his knowledge about all the animals and the rainforest. Read all
We had an amazing time in TRC. From the guide, tours, lounge staff, food and room, everything has exceeded our expectation and like an amazing dream came true. This is the only lounge available in Tambopata national park, and this eco lounge takes environment seriously. We highly recommend to directly book with the lounge website, so that you got a private guide for your group. Special thanks to our guide Saul, who made this experience extra special! We were so impressed by his knowledge about all the animals and the rainforest. If you are a natural lover, you can’t miss this place Read all
Excellent and luxurious place, wonderful experience and our guide Boris was first class, he had a unique patience with my 8 year old son. An experience in the tropical rainforest that marks the life of its visitors. In addition to the scientific research that takes place in the place: a whole research center. Rooms: Very comfortable and luxuriou Read all
El mejor hotel para visitar la Amazonia peruana. Hotel eco turístico metido en medio de la selva, equipado para visitar y vivir la selva, su flora y fauna, en todas sus facetas. Todo incluido, con guías preparados y amables, resultó una experiencia increíble para mi familia. Dentro de las opciones no se debe perder el Canopy de 45 metros de altura para observar y escuchar la selva, así como el lago de las tres Chimbadas, lugar único para ver caimanes, nutrias gigantes, monos y aves exóticas. Recomiendo mínimo dos noches!!! Read all
Wunderbare lodge mit freundlichen Menschen. sehr persönliche guides, tolle Tourangebote und super kulinarische Verpflegung ! Wir wurden herzlichst von Caesar empfangen und unser guide JuanJo hat uns phantastische Dinge gezeigt. Wir können die lodge nur wärmstens empfehlen! Read all
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